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Cytochrome P450 3A4 Interaction The concomitant use of Hydrocodone Bitartrate and Acetaminophen Tablets with all Cytochrome P450 3A4 inhibitors may result in an increase in hydrocodone plasma concentrations, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression

Int J Oncol (2007) 30:76574

Note: The diluent is normal saline (0.9% NaCl) or PBS (0.01 M, pH 7.4)

PS and BaP induce kidney damage in mice To monitor the health of the mice during drug administration, body weights and organ coefficients were measured and recorded on a weekly basis